Project MKOFTEN

Project MKOFTEN was a U.S. Central Intelligence Agency program conducted in cooperation with the Department of Defense, operating under the aegis of Project MKSEARCH, for the purpose of testing "the behavioral and toxicological effects of certain drugs on animals and humans." It is often conflated with Operation OFTEN, which reputedly focused primarily on investigating occultism and psychicism, and their potential uses in intelligence operations (and it is entirely possible OFTEN-linked programs may have simply been MKOFTEN subprojects).